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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERBB3 All Species: 23.64
Human Site: S1130 Identified Species: 47.27
UniProt: P21860 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21860 NP_001005915.1 1342 148098 S1130 S P R P R G D S A Y H S Q R H
Chimpanzee Pan troglodytes XP_509131 1342 148124 S1130 S P R P R G D S A Y H S Q R H
Rhesus Macaque Macaca mulatta XP_001113953 1342 148045 S1130 S P R P R G D S A Y H S Q R H
Dog Lupus familis XP_538226 1536 167696 S1324 S P R P R G D S A Y H S Q R H
Cat Felis silvestris
Mouse Mus musculus Q61526 1339 147594 S1127 S P R P R G D S A Y H S Q R H
Rat Rattus norvegicus Q62799 1339 147527 S1127 S P R P R G D S A Y H S Q R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508590 1260 141049 R1052 S G N Q F V Y R D G G F G A E
Chicken Gallus gallus P13387 703 77409 T495 F A T Q S Q K T K I I Q N R N
Frog Xenopus laevis NP_001089061 1299 145796 G1087 T E V P T A Q G A T A E V F D
Zebra Danio Brachydanio rerio NP_001122291 1429 159077 D1169 S K S T P K T D A T Q E Y E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04412 1426 159700 A1198 T T V F A E F A R D P G R Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P24348 1323 150493 N1111 N R L S Q P P N C S Q D L Y Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.7 81.1 N.A. 90.6 90.4 N.A. 48.3 25.9 47 48.4 N.A. 24.9 N.A. 21.1 N.A.
Protein Similarity: 100 99.9 99.2 83.1 N.A. 94.2 94.5 N.A. 63.9 35.2 63.3 61.6 N.A. 39.8 N.A. 38.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 6.6 13.3 13.3 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 20 20 13.3 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 0 9 67 0 9 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 50 9 9 9 0 9 0 0 9 % D
% Glu: 0 9 0 0 0 9 0 0 0 0 0 17 0 9 9 % E
% Phe: 9 0 0 9 9 0 9 0 0 0 0 9 0 9 0 % F
% Gly: 0 9 0 0 0 50 0 9 0 9 9 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 50 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % I
% Lys: 0 9 0 0 0 9 9 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 9 0 0 0 0 9 0 9 % N
% Pro: 0 50 0 59 9 9 9 0 0 0 9 0 0 0 0 % P
% Gln: 0 0 0 17 9 9 9 0 0 0 17 9 50 0 9 % Q
% Arg: 0 9 50 0 50 0 0 9 9 0 0 0 9 59 0 % R
% Ser: 67 0 9 9 9 0 0 50 0 9 0 50 0 0 0 % S
% Thr: 17 9 9 9 9 0 9 9 0 17 0 0 0 0 0 % T
% Val: 0 0 17 0 0 9 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 50 0 0 9 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _